CORDIS Project
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This project focuses on engineering bacteria to produce variants of the secondary metabolite resveratrol, aiming to understand its effects on the tumor suppressor protein p53 and its potential as a cancer therapy. It explores the relationship between protein dynamics and aggregation, particularly in the context of neur…
The project proposal aims to engineer a bacterial host to produce variants of secondary metabolite resveratrol and address the interrelationship between dynamics, structure and function of a system of high medical interest, the tumor suppressor protein p53.
The study considers to elucidate the mode of action of these molecules against the p53 mutants and work on new concepts for cancer therapy.
Inside the cell, the folding of a protein is a fast and robust process.
Sometimes, however, sudden cha…
TECHNISCHE UNIVERSITAET MUENCHEN
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Rensselaer Polytechnic Institute
United States, Troy
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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