CORDIS Project
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The PACI project investigates the adaptation of Pseudomonas aeruginosa in chronic infections, focusing on a mutant strain that produces a brown pigment. By analyzing genetic changes and their impact on virulence and antibiotic resistance, the project aims to improve treatment options for patients with respiratory infec…
Pseudomonas aeruginosa (PA) is an important bacterial pathogen causing a wide range of acute and chronic infections (CI).
It usually expresses a yellow-green pigment.
It is a major cause of respiratory CI in patients with underlying diseases such as cystic fibrosis (CF) leading to a progressive lung damage.
Pathogenesis in CI implies a genetic diversification of PA, with emergence of atypical mutants such as brown pigment producing PA (bpPA). PACI study aims to explore the adaptation process of…
UNIVERSITE DE FRANCHE-COMTE
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