CORDIS Project
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This project focuses on the structural analysis of the TRPV2 channel, a receptor involved in pain perception. Using advanced techniques like Cryo-Electron Microscopy and spectroscopy, it aims to understand TRPV2's structure and function, which could lead to new treatments for pain management.
The IOF call is a unique opportunity for the researcher to carry out this project.
Transient Receptor Potential channels are extremely interesting since some of them are receptors for pain (nociceptors).
The actual subject of research is the structural characterization of TRPV2, a nociceptor which responds to different stimuli such as cannabidiol, pressure and noxious heat. TRPV2 is expected to be a large membrane protein (potential homotetramer of ~400 KDa).
To study TRPV2’s 3D structure, singl…
UNIVERSITAT AUTONOMA DE BARCELONA
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