CORDIS Project
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The PANACHE project focuses on developing new inhibitors for specific membrane proteins involved in inflammation. By collaborating across disciplines, it aims to create treatments for inflammatory diseases affecting the cardiovascular system and liver.
The modulation of membrane-bound proteins by drugs is receiving increasing attention from both academia and industry.
Among such proteins are pannexin1 (Panx1), connexin43 (Cx43) and connexin32 (Cx32) that form hemichannels at the plasma membrane surface.
These hemichannels mediate cellular communication and have emerged as key players in inflammation.
This carries translational relevance, as hemichannel inhibition could represent an innovative strategy for the treatment of a plethora of disease…
VRIJE UNIVERSITEIT BRUSSEL
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Switzerland, Geneve
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
FUNDACION PUBLICA GALEGA DE INVESTIGACION BIOMEDICA INIBIC
Spain, A CORUNA
Type: Research institute
Activity type: Research Organisations
SME: No
Spain, VALENCIA
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
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