CORDIS Project
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This project investigates the role of pancreatic stellate cells in pancreatic ductal adenocarcinoma, a deadly form of cancer. It aims to understand how these cells contribute to tumor development and immune responses, potentially revealing new therapeutic targets.
Pancreatic ductal adenocarcinoma (PDA) is a lethal disease killing about 7000 people in the United Kingdom every year. PDA is resistant to conventional therapy. A hallmark of PDA is the abundance of desmoplastic stroma, which is thought to originate by activation of pancreatic stellate cells (PSC).
Unfortunately, little is know about the precise role of PSC in the physiology of the pancreas.
In this proposal I will investigate the function of the pancreatic stellate cell in health and during tum…
CANCER RESEARCH UK LBG
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