CORDIS Project
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This project aims to advance the understanding of RNA dynamics by developing new NMR techniques for studying micro-RNAs. It focuses on characterizing RNA conformational changes to improve insights into gene regulation and drug discovery.
Over the last decades, new discoveries have revealed an ever-increasing diversity of RNA functions, profoundly modifying the conceptual framework of molecular biology.
This is the case of micro-RNAs (miRNA), a fascinating class of small non-coding RNA that play essential roles in RNA induced gene silencing and are estimated to target up to 60% of protein-coding genes in humans.RNA functional diversity is often triggered by conformational changes, so capturing the dynamics of these molecules is k…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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