CORDIS Project
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This project focuses on understanding the DNA segregation process in bacteria, specifically the type II plasmid partitioning system. It aims to explore the molecular mechanisms of plasmid movement during cell division using advanced imaging techniques.
The segregation of newly replicated DNA is an essential process in all prokaryotes and eukaryotes, ensuring the propagation of DNA to daughter cells.
In bacteria, the plasmid partitioning system helps in the proper segregation of low copy number plasmids during cell division.
The type II plasmid partitioning system (ParMRC) consists of three major elements – a parC DNA site, which acts as a centromeric region, and two proteins, one of which (ParR) binds to the centromeric region, and the filamen…
MEDICAL RESEARCH COUNCIL
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