CORDIS Project
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This project focuses on understanding the role of specific microRNAs in heart hypertrophy, which is a key factor in heart failure. By investigating these microRNAs, the project aims to develop innovative therapies to reverse cardiac remodeling and improve heart health.
BACKGROUND:
There is a tremendous need to develop novel therapies for heart failure.
In particular, sustained pathological hypertrophy, a major predictor of this condition, is a complex process, which involves transcriptional and posttranscriptional regulation of the cardiac genome.
There is now clear indication that, besides a few known transcriptional regulators, multiple, still poorly understood cardiac factors are involved in hypertrophy; understanding this complexity is expected to pave to…
INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY
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