CORDIS Project
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This research focuses on understanding the complex interactions of factors contributing to Alzheimer's disease. It aims to develop new diagnostic tools to explore the disease's pathogenesis and identify potential therapeutic targets by examining amyloid beta and other related pathologies.
Critical to our understanding of Alzheimer’s disease (AD) and also to finding therapies is determining how key pathological factors interact and relate to neuronal toxicity, symptoms and disease progression.
My research has focussed on amyloid beta (Aβ) moities and demonstrated that cerebrospinal fluid (CSF) Aβ42 correlates with cerebral Aβ pathology; that Aβ accumulates in the brain 10-20 years prior to onset of symptoms; and that CSF Aβ abnormalities precede CSF tau changes.
However, it is inc…
UGOT - GOETEBORGS UNIVERSITET/UNIVERSITY OF GOTHENBURG
GOETEBORGS UNIVERSITET
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