CORDIS Project
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This project investigates how immunomodulatory molecules from the helminth parasite Fasciola hepatica can influence immune responses. It aims to explore their potential in promoting transplant tolerance and mitigating immune reactions in models of organ transplantation and graft versus host disease.
Pathogenic organisms such as bacteria, viruses and parasitic worms have evolved strategies to actively subvert the host immune system, facilitating their persistence.
As a consequence, the identification of specific pathogen derived immunomodulatory molecules has become an intense area of research with a number of such molecules having been found to offer potential as immunotherapeutics in animal models of autoimmune disease and allergy.
As there is considerable overlap between the cellular immu…
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
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