CORDIS Project
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This project investigates how B cells recognize antigens and behave within lymph nodes, utilizing advanced microscopy techniques. By analyzing the interactions and transport mechanisms in vivo, the research aims to enhance our understanding of B cell activation, which is crucial for developing effective therapeutic ant…
B cells produce antigen-specific antibodies as part of the adaptive immune response.
This is the result of a complex process of activation and differentiation that is initiated with the specific engagement of the Ag to the BCR.
While a wide range of studies have been performed in vitro to understand B cell-Ag recognition, we still understand very little about the basics of motility, compartimentalization and Ag recognition in vivo, because these events occur in densely packed lymphoid organs.
On…
CANCER RESEARCH UK LBG
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