CORDIS Project
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This project aims to enhance the understanding and treatment of primary biliary cirrhosis by investigating genetic and environmental factors. It focuses on developing personalized medicine approaches through the identification of molecular pathways and biomarkers for effective clinical applications.
Primary biliary cirrhosis (PBC) is the most prevalent of adult autoimmune liver diseases, seen in both genders and all ethnicities, but remains without rational treatment.
Its immune mediated liver injury is driven by interacting innate, humoral and cellular pathways, on a strong background of genetic and environmental risk.
Improved treatment is a priority for patients but is hindered by a) complexity inherent to composite genetic and environmental risks; b) inadequate understanding of molecula…
THE UNIVERSITY OF BIRMINGHAM
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