CORDIS Project
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The PCUBE project focuses on improving the production of functional proteins for structural biology research. It integrates high-throughput methods and existing infrastructures to facilitate efficient protein expression and crystallization.
The most important prerequisite and challenge in structural biology research at the atomic level by any method is the availability of sufficiently large amounts of highly purified functional proteins due to the increasing size and complexity of target proteins or protein complexes to be analyzed.
Heterologous expression in bacteria, yeast, insect, or mammalian cells combined with many attempts involving different DNA constructs that result in a large variety of protein variants is instrumental t…
University of Zurich
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United Kingdom, Oxford
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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