CORDIS Project
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This project aims to develop targeted peptide-drug conjugates to prevent weight regain after weight loss. By focusing on specific neurons in the brain that regulate hunger, it seeks to create effective treatments for maintaining weight loss in individuals.
The worldwide rise in obesity rates is causing significant harm to human health.
While effective weight loss therapies are emerging, the challenge of maintaining weight loss remains unresolved.
With this project, we will leverage expertise in drug development to engineer novel peptide-drug conjugates designed to obstruct homeostatic weight regain in a cell specific fashion.
In the food deprived state, a subset of hunger promoting neurons undergo structural changes that increases excitability and…
KOBENHAVNS UNIVERSITET
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