CORDIS Project
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The PDE4NPD project aims to develop a drug discovery platform targeting cyclic nucleotide phosphodiesterases to combat neglected parasitic diseases. By integrating phenotypic screening and compound optimization, it seeks to identify new treatments for diseases like sleeping sickness and Chagas' disease.
This project aims to unite global efforts to target the highly druggable class of enzymes called cyclic nucleotide phosphodiesterases (PDEs) in the fight for neglected parasitic diseases (NPD).
It will establish a drug discovery platform, PDE4NPD, that combines phenotypic screening with efficient target-centric drug discovery, including target validation, various strategies for compound screening, PDE hit and lead optimization, safety and toxicology assessments and evaluation of anti-parasitic a…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
United Kingdom, Glasgow
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
United Kingdom, Canterbury, Kent
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, Hamburg
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
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