CORDIS Project
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This project aims to explore the role of inflammation in the development of Parkinson's disease by studying immune cell interactions and genetic factors. Using advanced mouse models and stem cells, it seeks to identify early biomarkers and potential therapeutic targets for intervention.
Parkinson's disease (PD) is a relentlessly progressive disease characterized clinically by bradykinesia, rigidity, and resting tremor.
Clinical manifestations of PD are not apparent until 80~85% of neurons in the substantia nigra pars compacta (SNc) have degenerated and striatal dopamine (DA) levels are depleted by 60~80%.
At the time of diagnosis, the therapeutic window and the potential to intervene are therefore greatly reduced.
Thus, there is an urgent need to understand better the pathogene…
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