CORDIS Project
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This project explores the creation of self-replicating protocells using coacervation of self-templating peptides. By designing peptides that can form stable droplets, the research aims to understand mechanisms of self-replication and the origins of life.
One of the most fundamental questions in chemistry and biology is how a self-replicating protocell could form from collection of inanimate molecules.
Self-replicating RNA molecules in lipid compartments have been widely studied, but these systems are inherently unstable and a plausible mechanism for their spontaneous formation and repeated replication is still lacking.
Here, I propose to use coacervation of self-templating peptides as a radically new approach to create stable self-replicating pr…
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