CORDIS Project
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This project focuses on developing a personalized anti-cancer vaccine using a conditionally replicating adenovirus. The approach aims to enhance immune responses against tumors by coating the virus with tumor-specific peptides, thereby improving treatment efficacy.
This grant application proposes to develop a novel, customizable and personalized anti-cancer vaccine: peptide-coated conditionally replicating adenovirus (PeptiCrad).Anti-cancer vaccines represent a promising approach for cancer treatment because they elicit durable and specific immune response that destroys primary tumors and distant metastases.
Oncolytic viruses (OVs) are of significant interest because in addition to cytolysis they stimulate anti-tumor immune responses, thereby functioning a…
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