CORDIS Project
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This project focuses on developing bioadhesive hydrogels for bone regeneration, utilizing dihydroxyphenylalanine-based materials to enhance cell adhesion and mineralization. The aim is to create injectable systems that mimic natural bone healing processes for minimally invasive surgeries.
The shortcomings of current medical grafting procedures to treat severe bone defects continue to drive the development of alternative therapies.
The clinical success of synthetic bone fillers is still disappointingly limited.
Although hydrogels have not been classically studied for bone regeneration applications, owing to their inherently low mechanical properties, these highly hydrated soft materials can provide a proper environment to cell adhesion, migration, proliferation and differentiation…
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