CORDIS Project
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This project focuses on the role of specific cell types in tissue repair and fibrosis. It aims to understand how mesenchymal cells contribute to inflammation and scarring, which can lead to chronic diseases, and seeks to identify new therapeutic targets for treatment.
The survival of organisms requires the ability to repair tissues upon injury, as well as, after birth, to fight foreign invaders that may have contaminated the wound.
This last function is mediated by a complex host response involving immune cells, blood vessels and inflammatory mediators that collectively intend to neutralize the harmful agent and eliminate damaged/necrotic tissue.
Initially beneficial, this massive inflammatory response comes with a cost, and adult injured tissues usually heal…
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