CORDIS Project
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PEROXISCENCE investigates the quiescent state of fungi and its role in persistent infections. The project focuses on understanding lipid homeostasis and the mechanisms that allow fungi to survive under stress, aiming to identify new strategies to combat these infections.
Quiescence, a temporary cellular state of non-proliferation, is widespread in nature.
Quiescent fungi often cause persistent infections resistant to conventional treatments.
Quiescence is maintained via the consorted action of several regulatory pathways.
In yeast, these include stabilization of the eisosome-localized, ubiquinol-generating Flavodoxin-like proteins (FLPs), recently shown by my host labs to counteract ferroptosis, a form of iron-dependent cell death promoted by peroxidised phospho…
UNIVERSITE LIBRE DE BRUXELLES
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Belgium, Bruxelles / Brussel
Type: Public body
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
SME: No
Germany, MUENSTER
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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