CORDIS Project
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This project investigates the role of PHIST proteins in modifying red blood cells infected by malaria parasites. By employing advanced techniques, it aims to understand how these modifications affect the parasite's virulence and transmission to mosquitoes.
The malaria parasite is the ultimate home renovator, inducing drastic changes to the host red blood cell (RBC) important for virulence and sexual maturation.
Members of the PHIST protein family are involved RBC modification and while some are expressed in the sexual stages, their function is unknown.
To understand the significance of the extensive RBC alterations, the functional characterisation of the PHIST family is required.
To begin this task, we have carefully selected 10 PHIST proteins to…
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