CORDIS Project
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This project aims to understand the molecular mechanisms behind the formation of malaria gametocytes, which are crucial for the parasite's transmission. It focuses on developing techniques to isolate early-stage gametocytes and identify the signaling pathways involved in their development.
Malaria is a devastating disease caused by the apicomplexan parasite Plasmodium.
Plasmodium falciparum represents the most severe and life-threatening form of human malaria, causing over 500,000 deaths per year.
There is no efficient vaccine available and resistance to all currently used drugs reported.
One of the major problems in eradicating human malaria is the transmission of the parasites sexual stages, the gametocytes.
These are formed in the blood and develop through five different morpho…
THE FRANCIS CRICK INSTITUTE LIMITED
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