CORDIS Project
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This project investigates the role of phenolic glycolipids in the immune response to mycobacterial diseases like tuberculosis. By reprogramming a vaccine strain to produce specific glycolipids, the research aims to understand their interaction with immune cells and identify potential therapeutic targets.
Mycobacterial diseases, like tuberculosis and leprosy, are still a threat for public health.
Although antibiotherapy and BCG vaccine exist, they have failed to control these diseases.
It is hence crucial to improve our knowledge of the factors involved in mycobacterial pathogenesis to design new therapies.
The hallmark of mycobacterial pathogens is their ability to persist in the host by delaying the adaptive immune response.
Among the mycobacterial factors suspected to play a role are phenolic…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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