CORDIS Project
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This project investigates how specific bacteriophage integration affects bacterial hosts. By examining the evolutionary pressures on phage components, it aims to understand their role in bacterial genome editing and the dynamics of phage-host interactions.
Bacteriophages are found in over two-thirds of sequenced bacterial genomes, with phage DNA making up an estimated 10% of these genomes.
Recent studies suggest that phage DNA integration, during so called lysogeny, can lead to interactions with bacterial hosts that are more complex than once thought.
There are phages which very specifically and reversibly integrate into host genes, modulating host development.
Altering bacterial behaviours can have detrimental consequences in microbial communitie…
UNIVERZA V LJUBLJANI
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