CORDIS Project
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This project investigates the molecular mechanisms behind the formation and regulation of membraneless organelles in cells, focusing on the kinase DYRK3 and its interactions with phosphatases. It aims to understand how these processes relate to neurodegenerative diseases characterized by protein aggregation, potentiall…
As the demographics of Europe and other developed countries shift ever older, neurodegenerative diseases involving aberrant protein aggregation grow more common but still lack effective treatment options.
In healthy eukaryotic cells, the reversible weak aggregation of proteins and RNAs is necessary for the formation of condensates known as membraneless organelles.
The roles of these condensates are still under investigation but may include concentrating proteins to facilitate reactions and buffe…
UNIVERSITAT ZURICH
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