CORDIS Project
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The PhotoXLink project develops innovative optogenetic tools to study AMPA receptor dynamics in the brain, focusing on their role in learning and memory. By creating photocrosslinkers that manipulate AMPA receptor subunits, the project aims to enhance our understanding of synaptic plasticity in both healthy and disease…
The PhotoXLink project aims to develop original tools to elucidate the role of various AMPA receptor mediated forms of plasticity in both physiological and pathological situations. AMPAR is a transmembrane ionotropic receptor for glutamate molecule that mediates most fast excitatory synaptic transmission in the mammalian central nervous system.
Its regulation is vital for their synaptic function, which underlies memory and learning theories.
In the PhotoXLink project, we propose to engineer nove…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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