CORDIS Project
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The HostResponse project investigates mechanisms behind drug resistance in cancer therapy, aiming to develop a diagnostic platform that identifies patient-specific resistance factors. This platform will aid researchers and clinicians in optimizing treatment strategies against cancer.
Drug resistance is a major reason for failure in cancer chemotherapy and/or modern targeted drugs.
While tumours usually initially respond to therapy, resistance occurs within several cycles of treatments, or later on when patients are off therapy.
Until recently, acquired and intrinsic resistance mechanisms for therapy were thought to be solely tumour driven.
They are usually measured after tumours relapse or after several lines of treatments.
However, in our ERC starting grant (HostResponse N…
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