CORDIS Project
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This project investigates how mechanical forces from the tissue environment influence gene expression and multicellular behavior, focusing on breast cancer cells. By combining experiments and simulations, it aims to understand the role of mechanotransduction in tissue regeneration and disease, bridging the gap between…
There is growing evidence that mechanical forces emanating from the tissue microenvironment can activate biochemical signalling to control gene expression, in a process known as mechanotransduction, for tissue regeneration and organ development.
Importantly disruption of this effect by changes in the microenvironment leads to pathological responses including tissue fibrosis and cancer.The advent of new force measurement techniques and high-resolution microscopy have made it possible to isolate i…
KOBENHAVNS UNIVERSITET
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