CORDIS Project
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This project investigates the mechanochemistry of mitochondrial DNA replication and transcription using advanced single-molecule techniques. By studying the minimal genomic machinery, it aims to provide insights into the functioning of mitochondrial processes and related diseases.
I propose to unravel parts of the mechanochemistry of two key genome transactions: replication and transcription using an array of single-molecule techniques.
To this end, I propose to study the minimal genomic machinery of mitochondria.
Mitochondria are organelles in eukaryotic cells that contain their own DNA (mtDNA).
Significant understanding of the biochemistry of DNA transactions in mitochondria is obtained from the in vitro reconstitution of mitochondrial replication and transcription.
How…
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Netherlands, Amsterdam
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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