CORDIS Project
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This project examines the collective migration of neural crest cells, focusing on the mechanical forces involved in their movement. By comparing these cells to epithelial tissues, it aims to understand how temporary cell contacts facilitate coordinated migration during development.
Coordinated migration of cells is an important process in development and physiology.
Collective migration has been extensively studied in tightly connected cell sheets, or epithelia, with recent studies reporting forces in epithelial collective migration.
Although a physical and functional connection between the cells throughout the whole process has been thought necessary for collective migration, collective behaviour has recently been reported in the migration of loosely coherent neural crest…
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