CORDIS Project
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This project investigates the role of specific proteins in immune responses and their relationship to gut health. It focuses on understanding how certain immune cells process and present antigens, which is crucial for maintaining tolerance to gut microbiota and preventing inflammatory diseases.
PI3Ks controls important biological processes immunity controlling vesicular trafficking and cell signaling events triggered by pathogen recognition receptors (PRRs).
The engagement of PRRs leading to DC antigen processing and presentation (APP) is essential for the bridge between innate and adaptive immunity.
Thus, DCs are crucial for resistance against pathogens, while concurrently maintaining tolerance to the commensal microbiota and environmental antigens.
Crohn’s disease (CD)-like patholog…
QUEEN MARY UNIVERSITY OF LONDON
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