CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the dynamic regulation of interactions between Ras proteins and phosphoinositide 3-kinase (PI3K) in cancer and inflammation. By studying these interactions, the research aims to understand their role in cell signaling, cancer progression, and cellular senescence, ultimately exploring potential…
Ras genes take a center stage in signal transduction and molecular oncology, where Ras-driven signaling pathways control proliferation, differentiation, cell adhesion, apoptosis, and cell migration.
Mutations in RAS are very common in cancer, and have been found in 20-30% of all human tumors.
Moreover, constitutive Ras activation is known to trigger senescence in the absence of “second hit” mutations (e.g. loss of p53).
Interestingly, both processes - cancer progression and oncogene-induced cell…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
