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The PigSNP project focuses on identifying single nucleotide polymorphisms (SNPs) in commercial pig breeds using advanced sequencing techniques. By analyzing DNA from multiple individuals, it aims to enhance genomic selection and fine mapping of traits related to fatness and meat quality in breeding programs.
Within the PigSNP project SNPs will be identified that are known to be segregating within commercial European pig breeds.
Using the Solexa sequencing technique a representation of the genome is directly sequenced to high redundancy.
This is achieved by digesting the DNA with a restriction enzyme and sequencing fragments within a specific size range (i.e. 250 bp).
The strategy used is based on sequencing a mixture of the DNA from 5 individuals of a single commercial breed to 20 X depth.
Furthermo…
WAGENINGEN UNIVERSITY
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