CORDIS Project
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This project explores the role of inflammation in Type 2 diabetes, focusing on pancreatic cell function. It aims to understand how environmental and genetic factors disrupt inflammation, contributing to cell failure and diabetes progression.
Type 2 diabetes (T2D) has reached epidemic proportions, killing millions each year; however, our incomplete understanding of its etiology hinders the quest for a cure. T2D is caused by pancreatic -cell failure and insulin resistance.
Recent studies point to aberrant islet inflammation as a driver of diabetes.
While inflammation is beneficial for insulin secretion during homeostasis, it may transform to harm -cell function and impair the glucose response.
How islet inflammation maintains glucose…
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