CORDIS Project
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This project focuses on enhancing the imaging speed of DNA optical mapping to analyze the human gut microbiome. By employing plasmon-enhanced fluorescence, it aims to improve the efficiency of genetic information acquisition for better health diagnostics and personalized care.
Human microbiome science is advancing, showing promise of having important impacts on human health with new insights into disease etiology and general human biology.
Accordingly, DNA sequencing platforms have been developed rapidly, expanding the scope in microbiome research.
Among others, optical mapping technique, capable of imaging single DNA molecules provides access to genetic information on single molecules up to ~1 Mbp in length.
It uses fluorescence imaging of linearly stretched DNA mole…
KATHOLIEKE UNIVERSITEIT LEUVEN
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