CORDIS Project
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This project investigates the interactions between tumor cells and surrounding stromal cells in colorectal cancer, focusing on the plasticity of these cells and their roles in metastasis. By developing innovative tools and conducting in vivo screens, the project aims to uncover new pathways that could lead to better th…
Colorectal cancer (CRC) belongs to the most frequent tumor entities in both men and women.
Although early detection and certain therapies have improved, the prognosis for patients with metastatic diseases is dismal and survival rates are below 10% at 5 years after diagnosis.
Colorectal carcinogenesis is greatly dependent on the plasticity of both tumor cells as well as surrounding stromal cells within the tumor microenvironment.
Among the latter, both T cells as well as mesenchymal cells substan…
CHEMOTHERAPEUTISCHES FORSCHUNGSINSTITUT GEORG-SPEYER-HAUS STIFTUNG
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