CORDIS Project
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This project explores how differentiated cells can change their identity through a process called transdifferentiation. Using a model organism, it aims to identify the molecular networks and cellular conditions that facilitate this transformation.
How differentiated cells can change their identity is a fascinating question.
Indeed, natural interconversions between functionally distinct somatic cell types (aka transdifferentiation, Td) have been reported in species as diverse as jellyfish and mice, while experimentally induced reprogramming of differentiated cells has been demonstrated.
The relative ease with which cellular identities can be reprogrammed raises a number of exciting questions:
What mechanisms and steps allow a given cell, b…
CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE
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