CORDIS Project
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This project aims to enhance the structural analysis of biological molecules by integrating preparative native mass spectrometry with cryo-electron microscopy. It focuses on improving sample preparation to achieve high-resolution imaging of proteins and their complexes, which is crucial for understanding biological pro…
Precise structural, conformational, as well as chemical information of biological molecules forms the basis for comprehension and control of biological processes, including metabolism, pathological processes, and drug targeting.
Cryo-electron microscopy (cryo-EM) has evolved into one of the leading methods for structural characterisation of folded proteins and protein complexes reaching atomic resolution through averaging.
Thus, the unambiguous assignment of thousands of images to different olig…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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