CORDIS Project
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This research explores the conditions under which autoimmune attacks on neurons occur, particularly in narcolepsy with cataplexy. It aims to investigate the roles of specific proteins in the immune response and their implications for neurodegenerative disorders.
The goal of this research is to determine under which conditions an autoimmune attack on neurons can occur.
There is a growing interest in neuroimmunology, and data suggests that disorders such as Parkinson’s disease and schizophrenia have an autoimmune component.
The ideal disease for studying this phenomenon is, however, the sleep disorder narcolepsy with cataplexy (NC), where the hypocretin (hcrt) producing neurons in hypothalamus are lost.
Genetic and epidemiological evidence suggest that th…
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