CORDIS Project
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This project studies microsporidia, emerging fungal pathogens, to understand their unique infection mechanisms. By employing structural biology techniques, it aims to elucidate the polar tube's role in host invasion and develop genetic tools for further research in this underexplored area.
Microsporidia are opportunistic fungal pathogens that infect organisms as evolutionarily divergent as protists and mammals.
Due to their growing impact on the global food supply chain, the environment, and human health, these unusual spore-forming organisms have been classified as emerging pathogens of high priority.
Intriguing cell biological features that are central to microsporidian infectivity and pose challenges to drug development are poorly understood due to a lack of structural informat…
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