CORDIS Project
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This project investigates the mechanisms by which TRPV1 ion channels detect pain stimuli. By examining the activation processes of these channels, the research aims to enhance understanding of pain perception and inform the development of targeted pain relief therapies.
The somatosensory system detects and integrates a large array of noxious stimuli of highly divergent nature.
Members of the transient receptor potential (TRP) ion channel family play a pivotal role in the detection of innocuous and noxious stimuli, of both physical and chemical nature.
Thus, elucidating the gating mechanisms of these channels is essential for our understanding of somatosensation and nociception.
Taken the polymodal nature of those somatosensory TRP channels, our overall goal is…
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