CORDIS Project
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This project investigates how confinement affects the formation of crystal polymorphs, focusing on calcium carbonate. Using advanced microscopy techniques, it aims to understand the nucleation process and extend findings to other materials and pharmaceuticals.
Controlling the polymorph (crystal structure) of crystalline materials is of vital importance to both material science and the pharmaceutical industry.
Many crystal polymorphs are difficult to access, however, as polymorph is determined by both kinetics and thermodynamics.
Recently, it has been observed that precipitation of crystals in confinement often leads to the formation of unusual polymorphs.
For example, CaCO3 forms purely as aragonite when it is precipitated in small nano-pores.
These o…
UNIVERSITY OF LEEDS
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