CORDIS Project
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This project focuses on understanding the regulation of gene expression by the Polycomb repressive complex 2 in embryonic stem cells. It aims to explore how this complex interacts with other chromatin modifiers to control developmental genes and its implications in cancer.
Posttranslational modifications of histone proteins have emerged as central regulators of gene expression.
Through the factors that install, interpret, and erase them, histone marks control access to the genome, establishing chromatin environments that either support or counteract transcription.
The histone methyltransferase Polycomb repressive complex 2 (PRC2) is crucially involved in gene repression all throughout development and adulthood, and it is often misregulated in cancer.
Despite signi…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
United Kingdom, Edinburgh
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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