CORDIS Project
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This project investigates the role of the Prep1 gene in regulating insulin sensitivity and fat formation, which are crucial for understanding type 2 diabetes and obesity. By studying both animal models and human subjects, the project aims to identify potential therapeutic targets for treating metabolic disorders.
Type 2 diabets and obesity are related conditions representing major components of the metabolic syndrome and one of the most challenging health problems of this century, also because of their growing impact in childhood.
Different studies have identified PPAR-gamma coactivator-1 (PGC-1alpha) as a relevant type 2 diabetes susceptibility gene playing an important role in human obesity as well.
Subsequent investigations led to the discovery that p160MBP (MybBindingProtein) serves as a PGC-1alpha i…
IFOM-ISTITUTO FONDAZIONE DI ONCOLOGIA MOLECOLARE ETS
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Italy, Napoli
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Italy, MILANO
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITY OF EASTERN FINLAND (UEF)
Finland, KUOPIO
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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