CORDIS Project
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This project aims to enhance understanding of stomach cancer mechanisms linked to microbial infections, particularly Helicobacter pylori. By analyzing historical gastric biopsy samples, the research seeks to identify high-risk individuals and develop non-invasive tests for early detection and prevention strategies.
Stomach cancer is the 4th most common cancer and 2nd leading cause of cancer-related death worldwide.
The aim of this proposal is to deepen the understanding of mechanisms involved in microbe-induced gastric carcinogenesis, which will facilitate risk stratification for identification of high-risk groups and may offer new opportunities for pharmacological and probiotic prevention.
We hypothesize that novel H. pylori genotypic variation can predict carcinogenicity.
The cancer-causing H. pylori str…
KAROLINSKA INSTITUTET
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