CORDIS Project
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The PRIMA project investigates how mechanical changes in the heart after acute myocardial infarction affect blood vessel formation. By developing advanced models, it aims to enhance understanding of angiogenesis and identify strategies to regenerate the heart's microvasculature, ultimately improving patient recovery ou…
Acute myocardial infarction (AMI) is a significant global health issue.
Current therapies cannot regenerate the hearts of survivors, leading to frequent AMI recurrence and premature death.
Crucially, these therapies fail to induce sufficient blood vessel formation, i.e. angiogenesis, which is essential to regenerate the cardiac microvasculature.
Without this vasculature, cells repopulating the infarcted tissue cannot survive. A deeper understanding and better control of post-AMI angiogenesis wou…
TECHNISCHE UNIVERSITEIT EINDHOVEN
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