CORDIS Project
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The PRO-MOM project aims to develop a postbiotic supplement to restore gut microbiota after antibiotic use during pregnancy and breastfeeding. This approach seeks to mitigate behavioral disturbances in offspring during critical early development.
Microbial dysbiosis can lead to behavioral changes including aggressive behavior.
Mice treated with antibiotics exhibit increased aggression, as do offspring of mothers given antibiotics only during pregnancy or alternatively only when nursing.
Promising results from our lab in flies and mice support our hypothesis that such behaviors are partially affected by gut bacteria and associated metabolic compounds.
Pregnancy is associated with reduced immune function and women receive antibiotics durin…
BAR ILAN UNIVERSITY
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