CORDIS Project
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This project aims to develop vaccines and monoclonal antibodies that can neutralize current and future variants of SARS-CoV-2 and other coronaviruses. By targeting less variable regions of the virus, the project seeks to create broadly protective interventions that can adapt to emerging threats.
The COVID-19 pandemic caught the world unprepared.
Vaccines and monoclonal antibodies (mAbs), developed in record time, mitigated the health and economic damages, however our reaction has always been one step behind the virus evolution, and emerging variants repeatedly escaped our interventions.
The omicron variant escaped humoral immunity generated by most vaccines and mAbs by mutating immunodominant epitopes.
The extremely potent mAb developed by our laboratory also lost potency against omicro…
FONDAZIONE TOSCANA LIFE SCIENCES
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