CORDIS Project
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This project investigates the repeatability of bacterial evolution towards antibiotic resistance by analyzing genetic changes in drug-resistance enzymes. It employs high-throughput experiments to understand mutation pathways and aims to develop strategies to anticipate and prevent the emergence of resistant bacterial s…
The fast evolution of bacterial pathogens towards antibiotic resistance is estimated by 2050 to be killing 10 million people every year.
Consequently, much interest is being directed towards finding ways to curb or even arrest this evolutionary process.
Of note, sequencing efforts are revealing that many of the genetic changes that drive resistance evolution are often repeatable.
Understanding what drives this repeatability is of foremost importance if we ever want to develop interventions aimed…
UNIVERSIDAD POLITECNICA DE MADRID
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